Miguel Sano/3B/Twins- The former mega-prospect's minor league career was both well-documented and watched. After a big rookie season in 2015, the future could not have looked any bigger or brighter for the young Miguel Sano. A disappointing 2016 changed all of that. The Twins made the head scratching decision to try Sano in the outfield due to the corner infield logjam and it was a disaster. Sano was moved back to third base mid-season and looked better, but suffered through some injury issues. The Twins released Trevor Plouffe at the end of the season, and Sano now has no road blocks, and hopefully no injuries, preventing him from having a BIG 2017.
Jose Berrios/SP/Twins- The second of three Twins on this list is starting pitcher Jose Berrios. After an up and down rookie season, Berrios will go to Spring Training with an opportunity to win a rotation spot right out of the gate. This guy is just too good not to. Berrios has a big 2017 written all over him.
Byron Buxton/CF/Twins- The third of three Twins on this list and I could have probably included more. This Twins team is so young, and so super-talented, the Twins 2016 season was one of the most inexplicable phenomenons in sports history. In terms of 25 man roster talent, good grief. The starting pitching was a little iffy, but talents Tyler Jay, Stephen Gonslaves, and Kohl Stewart are all expected to debut in 2017. Buxton is a former number one overall prospect who has had some injury issues the last couple of years. If he can put those injuries behind him, he is due for a big 2017 as well.
Orlando Arcia/SS/Brewers- The lone Brewer on this list, Arcia finished the season as the Brewers shortstop. He will be expected to be the opening day shortstop for the Brewers in 2017. Arcia is a mega-talent and it is only a matter of time before he explodes into an All-Star at the Major League level.
Tyler Glasnow/SP/Pirates- Glasnow was called up in 2016 and pitched briefly, going 0-2. That means very little. Standing 6'8”, 220 pounds, Glasnow has Major League ace written all over his face, and it is only a matter of time before he becomes one.
Alex Reyes/SP/Cardinals- The best Cardinals prospect, Reyes went 4-1 with a 1.57 late in 2016 in a call up for the Cardinals. With an aging Adam Wainwright, it is only a matter of time before the young Reyes makes his way to the top of the rotation in St. Louis.
Yoan Moncada/2B/White Sox- The return centerpiece in the big off-season trade that sent Chris Sale to the Red Sox, Moncada was considered to the best prospect in the game in 2016. He played briefly for the Red Sox at the end of the season, and will be expected to be the White Sox opening day second basemen in 2017.